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Helper T Cell (CD4(+)) Targeted Tacrolimus Delivery Mediates Precise Suppression of Allogeneic Humoral Immunity

Antibody-mediated rejection (ABMR) is a major cause of dysfunction and loss of transplanted kidney. The current treatments for ABMR involve nonspecific inhibition and clearance of T/B cells or plasma cells. However, the prognosis of patients following current treatment is poor. T follicular helper c...

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Detalles Bibliográficos
Autores principales: Shen, Jia, Liu, Chang, Yan, Pengpeng, Wang, Meifang, Guo, Luying, Liu, Shuaihui, Chen, Jianghua, Rosenholm, Jessica M., Huang, Hongfeng, Wang, Rending, Zhang, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343082/
https://www.ncbi.nlm.nih.gov/pubmed/35958106
http://dx.doi.org/10.34133/2022/9794235