Elucidating the importance and regulation of key enhancers for human MEIS1 expression

Myeloid ecotropic virus insertion site 1 (MEIS1) is essential for normal hematopoiesis and is a critical factor in the pathogenesis of a large subset of acute myeloid leukemia (AML). Despite the clinical relevance of MEIS1, its regulation is largely unknown. To understand the transcriptional regulat...

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Detalles Bibliográficos
Autores principales: Xiang, Ping, Yang, Xining, Escano, Leo, Dhillon, Ishpreet, Schneider, Edith, Clemans-Gibbon, Jack, Wei, Wei, Wong, Jasper, Wang, Simon Xufeng, Tam, Derek, Deng, Yu, Yung, Eric, Morin, Gregg B., Hoodless, Pamela A., Hirst, Martin, Karsan, Aly, Kuchenbauer, Florian, Humphries, R. Keith, Rouhi, Arefeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343249/
https://www.ncbi.nlm.nih.gov/pubmed/35624144
http://dx.doi.org/10.1038/s41375-022-01602-4

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