Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition

The standard front-line treatment for pleural mesothelioma (PM) is pemetrexed-based chemotherapy, whose major target is thymidylate synthase (TS). In several cancer models, miR-215 and miR-375 have been shown to target TS, while information on these miRNAs in PM are still limited although suggest th...

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Detalles Bibliográficos
Autores principales: Napoli, Francesca, Rapa, Ida, Izzo, Stefania, Rigutto, Angelica, Libener, Roberta, Riganti, Chiara, Bironzo, Paolo, Taulli, Riccardo, Papotti, Mauro, Volante, Marco, Scagliotti, Giorgio, Righi, Luisella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343276/
https://www.ncbi.nlm.nih.gov/pubmed/35461395
http://dx.doi.org/10.1007/s00428-022-03321-8

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