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microRNA-21-5p from M2 macrophage-derived extracellular vesicles promotes the differentiation and activity of pancreatic cancer stem cells by mediating KLF3

AIM: Given the fact that tumor-associated macrophage-derived extracellular vesicles (EVs) are attributable to tumor aggressiveness, this research intends to decode the mechanism of M2 macrophage-derived EVs in the differentiation and activities of pancreatic cancer (PaCa) stem cells via delivering m...

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Detalles Bibliográficos
Autores principales: Chang, Jian, Li, Hanjun, Zhu, Zhongchao, Mei, Pei, Hu, Weimin, Xiong, Xingcheng, Tao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343318/
https://www.ncbi.nlm.nih.gov/pubmed/33728488
http://dx.doi.org/10.1007/s10565-021-09597-x