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Highly conserved shifts in ubiquitin-proteasome system (UPS) activity drive mitochondrial remodeling during quiescence

Defects in cellular proteostasis and mitochondrial function drive many aspects of infertility, cancer, and other age-related diseases. All of these conditions rely on quiescent cells, such as oocytes and adult stem cells, that reduce their activity and remain dormant as part of their roles in tissue...

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Detalles Bibliográficos
Autores principales:	Yue, Sibiao, Wang, Lei, DeMartino, George N., Zhao, FangZhou, Liu, Yi, Sieber, Matthew H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343427/ https://www.ncbi.nlm.nih.gov/pubmed/35915093 http://dx.doi.org/10.1038/s41467-022-32206-2

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