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GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages

The putative medium-chain free fatty acid receptor GPR84 is a G protein-coupled receptor primarily expressed in myeloid cells that constitute the innate immune system, including neutrophils, monocytes, and macrophages in the periphery and microglia in the brain. The fact that GPR84 expression in leu...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Chen, Lin-hai, Yang, Hui, Fang, You-chen, Wang, Si-wei, Wang, Min, Yuan, Qian-ting, Wu, Wei, Zhang, Yang-ming, Liu, Zhan-ju, Nan, Fa-jun, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343429/
https://www.ncbi.nlm.nih.gov/pubmed/34912006
http://dx.doi.org/10.1038/s41401-021-00825-y