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GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
The putative medium-chain free fatty acid receptor GPR84 is a G protein-coupled receptor primarily expressed in myeloid cells that constitute the innate immune system, including neutrophils, monocytes, and macrophages in the periphery and microglia in the brain. The fact that GPR84 expression in leu...
Autores principales: | Zhang, Qing, Chen, Lin-hai, Yang, Hui, Fang, You-chen, Wang, Si-wei, Wang, Min, Yuan, Qian-ting, Wu, Wei, Zhang, Yang-ming, Liu, Zhan-ju, Nan, Fa-jun, Xie, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343429/ https://www.ncbi.nlm.nih.gov/pubmed/34912006 http://dx.doi.org/10.1038/s41401-021-00825-y |
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