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A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors
β-catenin-dependent canonical Wnt signaling plays a plethora of roles in neocortex (Ncx) development, but its function in regulating the abundance of intermediate progenitors (IPs) is elusive. Here we identified neCtnnb1, an evolutionarily conserved cis-regulatory element with typical enhancer featu...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343459/ https://www.ncbi.nlm.nih.gov/pubmed/35915089 http://dx.doi.org/10.1038/s41421-022-00421-2 |