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A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors

β-catenin-dependent canonical Wnt signaling plays a plethora of roles in neocortex (Ncx) development, but its function in regulating the abundance of intermediate progenitors (IPs) is elusive. Here we identified neCtnnb1, an evolutionarily conserved cis-regulatory element with typical enhancer featu...

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Detalles Bibliográficos
Autores principales: Wang, Junbao, Wang, Andi, Tian, Kuan, Hua, Xiaojiao, Zhang, Bo, Zheng, Yue, Kong, Xiangfei, Li, Wei, Xu, Lichao, Wang, Juan, Li, Zhiqiang, Liu, Ying, Zhou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343459/
https://www.ncbi.nlm.nih.gov/pubmed/35915089
http://dx.doi.org/10.1038/s41421-022-00421-2