NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury

Acute kidney injury (AKI) with maladaptive tubular repair leads to renal fibrosis and progresses to chronic kidney disease (CKD). At present, there is no curative drug to interrupt AKI-to-CKD progression. The nuclear factor of the activated T cell (NFAT) family was initially identified as a transcri...

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Detalles Bibliográficos
Autores principales: Xie, Zhi-yong, Dong, Wei, Zhang, Li, Wang, Meng-jie, Xiao, Zhen-meng, Zhang, Yu-hua, Shi, Wan-xin, Huang, Ying, Yang, Yan, Li, Cui-li, Fu, Lei, Zhao, Xing-chen, Li, Rui-zhao, Li, Zhi-lian, Chen, Yuan-han, Ye, Zhi-ming, Liu, Shuang-xin, Dong, Zheng, Liang, Xin-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343462/
https://www.ncbi.nlm.nih.gov/pubmed/34937917
http://dx.doi.org/10.1038/s41401-021-00833-y

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