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In vitro reversal of direct factor Xa inhibitors: Direct comparison of andexanet alfa and prothrombin complex concentrates Cofact and Beriplex/Kcentra

BACKGROUND: Both andexanet alfa and four‐factor prothrombin complex concentrate (4F‐PCC) are clinically applied reversal agents for direct factor Xa inhibitors (FXaIs) in emergency situations. Controversy exists whether 4F‐PCC is as effective as andexanet alfa in correcting FXaI anticoagulation. OBJ...

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Detalles Bibliográficos
Autores principales:	Brinkman, Herm Jan M., Zuurveld, Marleen, Meijers, Joost C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343596/ https://www.ncbi.nlm.nih.gov/pubmed/35928523 http://dx.doi.org/10.1002/rth2.12775

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