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Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data

D-dimer level is often used to assess the severity of trauma as well as the risk of thrombosis. This study investigated the risk factors for high postoperative D-dimer level. This study included a total of 2706 patients undergoing breast cancer surgery to examine the associations between various cli...

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Autores principales: Wang, Yanqiu, Liang, Xi, Wang, Shujun, Wang, Yuying, Qin, Ling, Chen, Danni, Jiang, Yanlin, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343692/
https://www.ncbi.nlm.nih.gov/pubmed/35928882
http://dx.doi.org/10.3389/fonc.2022.772726
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author Wang, Yanqiu
Liang, Xi
Wang, Shujun
Wang, Yuying
Qin, Ling
Chen, Danni
Jiang, Yanlin
Zhang, Hao
author_facet Wang, Yanqiu
Liang, Xi
Wang, Shujun
Wang, Yuying
Qin, Ling
Chen, Danni
Jiang, Yanlin
Zhang, Hao
author_sort Wang, Yanqiu
collection PubMed
description D-dimer level is often used to assess the severity of trauma as well as the risk of thrombosis. This study investigated the risk factors for high postoperative D-dimer level. This study included a total of 2706 patients undergoing breast cancer surgery to examine the associations between various clinicopathological factors and variation in D-dimer levels. After adjusting for other factors, T stage, neoadjuvant chemotherapy, blood loss, surgery type, diabetes, and elevated leukocyte and neutrophil counts were found to be significant risk factors for D-dimer variation. This study identified several factors associated with elevated D-dimer levels and consequent thrombosis after breast cancer surgery, which may aid in the development of more precise preventive measures and interventions as well as serve as a reference for future research.
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spelling pubmed-93436922022-08-03 Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data Wang, Yanqiu Liang, Xi Wang, Shujun Wang, Yuying Qin, Ling Chen, Danni Jiang, Yanlin Zhang, Hao Front Oncol Oncology D-dimer level is often used to assess the severity of trauma as well as the risk of thrombosis. This study investigated the risk factors for high postoperative D-dimer level. This study included a total of 2706 patients undergoing breast cancer surgery to examine the associations between various clinicopathological factors and variation in D-dimer levels. After adjusting for other factors, T stage, neoadjuvant chemotherapy, blood loss, surgery type, diabetes, and elevated leukocyte and neutrophil counts were found to be significant risk factors for D-dimer variation. This study identified several factors associated with elevated D-dimer levels and consequent thrombosis after breast cancer surgery, which may aid in the development of more precise preventive measures and interventions as well as serve as a reference for future research. Frontiers Media S.A. 2022-07-19 /pmc/articles/PMC9343692/ /pubmed/35928882 http://dx.doi.org/10.3389/fonc.2022.772726 Text en Copyright © 2022 Wang, Liang, Wang, Wang, Qin, Chen, Jiang and Zhang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Wang, Yanqiu
Liang, Xi
Wang, Shujun
Wang, Yuying
Qin, Ling
Chen, Danni
Jiang, Yanlin
Zhang, Hao
Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data
title Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data
title_full Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data
title_fullStr Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data
title_full_unstemmed Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data
title_short Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data
title_sort analysis of the risk factors for elevated d-dimer level after breast cancer surgery: a multicenter study based on nursing follow-up data
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343692/
https://www.ncbi.nlm.nih.gov/pubmed/35928882
http://dx.doi.org/10.3389/fonc.2022.772726
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