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Dietary compounds in modulation of gut microbiota-derived metabolites
Gut microbiota, a group of microorganisms that live in the gastrointestinal tract, plays important roles in health and disease. One mechanism that gut microbiota in modulation of the functions of hosts is achieved through synthesizing and releasing a series of metabolites such as short-chain fatty a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343712/ https://www.ncbi.nlm.nih.gov/pubmed/35928846 http://dx.doi.org/10.3389/fnut.2022.939571 |
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author | Feng, Wuwen Liu, Juan Cheng, Hao Zhang, Dandan Tan, Yuzhu Peng, Cheng |
author_facet | Feng, Wuwen Liu, Juan Cheng, Hao Zhang, Dandan Tan, Yuzhu Peng, Cheng |
author_sort | Feng, Wuwen |
collection | PubMed |
description | Gut microbiota, a group of microorganisms that live in the gastrointestinal tract, plays important roles in health and disease. One mechanism that gut microbiota in modulation of the functions of hosts is achieved through synthesizing and releasing a series of metabolites such as short-chain fatty acids. In recent years, increasing evidence has indicated that dietary compounds can interact with gut microbiota. On one hand, dietary compounds can modulate the composition and function of gut microbiota; on the other hand, gut microbiota can metabolize the dietary compounds. Although there are several reviews on gut microbiota and diets, there is no focused review on the effects of dietary compounds on gut microbiota-derived metabolites. In this review, we first briefly discussed the types of gut microbiota metabolites, their origins, and the reasons that dietary compounds can interact with gut microbiota. Then, focusing on gut microbiota-derived compounds, we discussed the effects of dietary compounds on gut microbiota-derived compounds and the following effects on health. Furthermore, we give our perspectives on the research direction of the related research fields. Understanding the roles of dietary compounds on gut microbiota-derived metabolites will expand our knowledge of how diets affect the host health and disease, thus eventually enable the personalized diets and nutrients. |
format | Online Article Text |
id | pubmed-9343712 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93437122022-08-03 Dietary compounds in modulation of gut microbiota-derived metabolites Feng, Wuwen Liu, Juan Cheng, Hao Zhang, Dandan Tan, Yuzhu Peng, Cheng Front Nutr Nutrition Gut microbiota, a group of microorganisms that live in the gastrointestinal tract, plays important roles in health and disease. One mechanism that gut microbiota in modulation of the functions of hosts is achieved through synthesizing and releasing a series of metabolites such as short-chain fatty acids. In recent years, increasing evidence has indicated that dietary compounds can interact with gut microbiota. On one hand, dietary compounds can modulate the composition and function of gut microbiota; on the other hand, gut microbiota can metabolize the dietary compounds. Although there are several reviews on gut microbiota and diets, there is no focused review on the effects of dietary compounds on gut microbiota-derived metabolites. In this review, we first briefly discussed the types of gut microbiota metabolites, their origins, and the reasons that dietary compounds can interact with gut microbiota. Then, focusing on gut microbiota-derived compounds, we discussed the effects of dietary compounds on gut microbiota-derived compounds and the following effects on health. Furthermore, we give our perspectives on the research direction of the related research fields. Understanding the roles of dietary compounds on gut microbiota-derived metabolites will expand our knowledge of how diets affect the host health and disease, thus eventually enable the personalized diets and nutrients. Frontiers Media S.A. 2022-07-19 /pmc/articles/PMC9343712/ /pubmed/35928846 http://dx.doi.org/10.3389/fnut.2022.939571 Text en Copyright © 2022 Feng, Liu, Cheng, Zhang, Tan and Peng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Feng, Wuwen Liu, Juan Cheng, Hao Zhang, Dandan Tan, Yuzhu Peng, Cheng Dietary compounds in modulation of gut microbiota-derived metabolites |
title | Dietary compounds in modulation of gut microbiota-derived metabolites |
title_full | Dietary compounds in modulation of gut microbiota-derived metabolites |
title_fullStr | Dietary compounds in modulation of gut microbiota-derived metabolites |
title_full_unstemmed | Dietary compounds in modulation of gut microbiota-derived metabolites |
title_short | Dietary compounds in modulation of gut microbiota-derived metabolites |
title_sort | dietary compounds in modulation of gut microbiota-derived metabolites |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343712/ https://www.ncbi.nlm.nih.gov/pubmed/35928846 http://dx.doi.org/10.3389/fnut.2022.939571 |
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