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Comparative Pharmacokinetics and Local Tolerance of Tenofovir Alafenamide (TAF) From Subcutaneous Implant in Rabbits, Dogs, and Macaques

The administration of antiretrovirals (ARVs) for HIV pre-exposure prophylaxis (PrEP) is highly efficacious and may benefit from new long-acting (LA) drug delivery approaches. This paper describes a subcutaneous, reservoir-style implant for the LA delivery of tenofovir alafenamide (TAF) and documents...

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Detalles Bibliográficos
Autores principales:	Gatto, G. J., Krovi, A., Li, L., Massud, I., Holder, A., Gary, J., Mills, P., Mitchell, J., Luecke, E., Demkovich, Z. R., Heneine, W., García-Lerma, J. G., Marzinke, M. A., Brand, R. M., Dobard, C. W., Johnson, L. M., Van Der Straten, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343794/ https://www.ncbi.nlm.nih.gov/pubmed/35928266 http://dx.doi.org/10.3389/fphar.2022.923954

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