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Platelet depletion does not alter long-term functional outcome after cerebral ischaemia in mice

Platelets are key mediators of thrombus formation and inflammation during the acute phase of ischaemic stroke. Particularly, the platelet glycoprotein (GP) receptors GPIbα and GPVI have been shown to mediate platelet adhesion and activation in the ischaemic brain. GPIbα and GPVI blockade could reduc...

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Detalles Bibliográficos
Autores principales: Steubing, Rebecca D., Szepanowski, Fabian, David, Christina, Mohamud Yusuf, Ayan, Mencl, Stine, Mausberg, Anne-Kathrin, Langer, Harald F., Sauter, Manuela, Deuschl, Cornelius, Forsting, Michael, Fender, Anke C., Hermann, Dirk M., Casas, Ana I., Langhauser, Friederike, Kleinschnitz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343933/
https://www.ncbi.nlm.nih.gov/pubmed/35928516
http://dx.doi.org/10.1016/j.bbih.2022.100493