TRPM7 channel inhibition attenuates rheumatoid arthritis articular chondrocyte ferroptosis by suppression of the PKCα-NOX4 axis

A role for ferroptosis in articular cartilage destruction associated with rheumatoid arthritis (RA) has not been identified. We previously reported transient receptor potential melastatin 7 (TRPM7) expression was correlated with RA cartilage destruction. Herein, we further characterized a role for T...

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Detalles Bibliográficos
Autores principales: Zhou, Renpeng, Chen, Yong, Li, Shufang, Wei, Xin, Hu, Weirong, Tang, Su'an, Ding, Jie, Fu, Wanjin, Zhang, Hailin, Chen, Fan, Hao, Wenjuan, Lin, Yi, Zhu, Rendi, Wang, Ke, Dong, Lei, Zhao, Yingjie, Feng, Xiaowen, Chen, Feihu, Ding, Changhai, Hu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344030/
https://www.ncbi.nlm.nih.gov/pubmed/35917680
http://dx.doi.org/10.1016/j.redox.2022.102411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344030/
https://www.ncbi.nlm.nih.gov/pubmed/35917680
http://dx.doi.org/10.1016/j.redox.2022.102411

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