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Case Report: Progression of a Silent Corticotroph Tumor to an Aggressive Secreting Corticotroph Tumor, Treated by Temozolomide. Changes in the Clinic, the Pathology, and the β-Catenin and α-SMA Expression
Clinically silent corticotroph tumors are usually macroadenomas that comprise 20% of ACTH tumors. They frequently progress to aggressive tumors with high recurrence, invasiveness, and on rare occasions, they may become hormonally active causing Cushing’s disease. Trustable biomarkers that can predic...
Autores principales: | Demarchi, Gianina, Perrone, Sofía, Esper Romero, Gaela, De Bonis, Cristian, Casasco, Juan Pablo, Sevlever, Gustavo, Berner, Silvia Ines, Cristina, Carolina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344046/ https://www.ncbi.nlm.nih.gov/pubmed/35928898 http://dx.doi.org/10.3389/fendo.2022.870172 |
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