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Datasets for a simulated family-based exome-sequencing study

We present simulated exome-sequencing data for 150 families from a North American admixed population, ascertained to contain at least four members affected with lymphoid cancer. These data include information on the ascertained families as well as single-nucleotide variants on the exome of affected...

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Detalles Bibliográficos
Autores principales: Epasinghege Dona, Nirodha, Graham, Jinko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344320/
https://www.ncbi.nlm.nih.gov/pubmed/35928588
http://dx.doi.org/10.1016/j.dib.2022.108311
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author Epasinghege Dona, Nirodha
Graham, Jinko
author_facet Epasinghege Dona, Nirodha
Graham, Jinko
author_sort Epasinghege Dona, Nirodha
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description We present simulated exome-sequencing data for 150 families from a North American admixed population, ascertained to contain at least four members affected with lymphoid cancer. These data include information on the ascertained families as well as single-nucleotide variants on the exome of affected family members. We provide a brief overview of the simulation steps and links to the associated software scripts. The resulting data are useful to identify genomic patterns and disease inheritance in families with multiple disease-affected members.
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spelling pubmed-93443202022-08-03 Datasets for a simulated family-based exome-sequencing study Epasinghege Dona, Nirodha Graham, Jinko Data Brief Data Article We present simulated exome-sequencing data for 150 families from a North American admixed population, ascertained to contain at least four members affected with lymphoid cancer. These data include information on the ascertained families as well as single-nucleotide variants on the exome of affected family members. We provide a brief overview of the simulation steps and links to the associated software scripts. The resulting data are useful to identify genomic patterns and disease inheritance in families with multiple disease-affected members. Elsevier 2022-05-26 /pmc/articles/PMC9344320/ /pubmed/35928588 http://dx.doi.org/10.1016/j.dib.2022.108311 Text en © 2022 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Data Article
Epasinghege Dona, Nirodha
Graham, Jinko
Datasets for a simulated family-based exome-sequencing study
title Datasets for a simulated family-based exome-sequencing study
title_full Datasets for a simulated family-based exome-sequencing study
title_fullStr Datasets for a simulated family-based exome-sequencing study
title_full_unstemmed Datasets for a simulated family-based exome-sequencing study
title_short Datasets for a simulated family-based exome-sequencing study
title_sort datasets for a simulated family-based exome-sequencing study
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344320/
https://www.ncbi.nlm.nih.gov/pubmed/35928588
http://dx.doi.org/10.1016/j.dib.2022.108311
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