Cargando…

Diet-induced obesity impairs spermatogenesis: the critical role of NLRP3 in Sertoli cells

BACKGROUND: Accumulating evidence indicates a key role of Sertoli cell (SC) malfunction in spermatogenesis impairment induced by obesity. Nucleotide-binding oligomerization domain-like receptor with a pyrin domain 3 (NLRP3) is expressed in SCs, but the role of NLRP3 in the pathological process of ob...

Descripción completa

Detalles Bibliográficos
Autores principales: Mu, Yang, Yin, Tai-lang, Zhang, Yan, Yang, Jing, Wu, Yan-ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344614/
https://www.ncbi.nlm.nih.gov/pubmed/35915511
http://dx.doi.org/10.1186/s41232-022-00203-z