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BTApep-TAT peptide inhibits ADP-ribosylation of BORIS to induce DNA damage in cancer

BACKGROUND: Brother of regulator of imprinted sites (BORIS) is expressed in most cancers and often associated with short survival and poor prognosis in patients. BORIS inhibits apoptosis and promotes proliferation of cancer cells. However, its mechanism of action has not been elucidated, and there i...

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Detalles Bibliográficos
Autores principales: Zhang, Yanmei, Fang, Mengdie, Li, Shouye, Xu, Hao, Ren, Juan, Tu, Linglan, Zuo, Bowen, Yao, Wanxin, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344678/
https://www.ncbi.nlm.nih.gov/pubmed/35918747
http://dx.doi.org/10.1186/s12943-022-01621-w