Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update

Ocular drug delivery is one of the most challenging endeavors among the various available drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic disease, we have not yet succeeded in achieving a proper drug delivery approach with the least adverse effects. Nanotechnolog...

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Autores principales: Afarid, Mehrdad, Mahmoodi, Shirin, Baghban, Roghayyeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344723/
https://www.ncbi.nlm.nih.gov/pubmed/35918688
http://dx.doi.org/10.1186/s12951-022-01567-7
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author Afarid, Mehrdad
Mahmoodi, Shirin
Baghban, Roghayyeh
author_facet Afarid, Mehrdad
Mahmoodi, Shirin
Baghban, Roghayyeh
author_sort Afarid, Mehrdad
collection PubMed
description Ocular drug delivery is one of the most challenging endeavors among the various available drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic disease, we have not yet succeeded in achieving a proper drug delivery approach with the least adverse effects. Nanotechnology offers great opportunities to overwhelm the restrictions of common ocular delivery systems, including low therapeutic effects and adverse effects because of invasive surgery or systemic exposure. The present review is dedicated to highlighting and updating the recent achievements of nano-based technologies for ocular disease diagnosis and treatment. While further effort remains, the progress illustrated here might pave the way to new and very useful ocular nanomedicines.
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spelling pubmed-93447232022-08-03 Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update Afarid, Mehrdad Mahmoodi, Shirin Baghban, Roghayyeh J Nanobiotechnology Review Ocular drug delivery is one of the most challenging endeavors among the various available drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic disease, we have not yet succeeded in achieving a proper drug delivery approach with the least adverse effects. Nanotechnology offers great opportunities to overwhelm the restrictions of common ocular delivery systems, including low therapeutic effects and adverse effects because of invasive surgery or systemic exposure. The present review is dedicated to highlighting and updating the recent achievements of nano-based technologies for ocular disease diagnosis and treatment. While further effort remains, the progress illustrated here might pave the way to new and very useful ocular nanomedicines. BioMed Central 2022-08-02 /pmc/articles/PMC9344723/ /pubmed/35918688 http://dx.doi.org/10.1186/s12951-022-01567-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Afarid, Mehrdad
Mahmoodi, Shirin
Baghban, Roghayyeh
Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
title Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
title_full Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
title_fullStr Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
title_full_unstemmed Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
title_short Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
title_sort recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344723/
https://www.ncbi.nlm.nih.gov/pubmed/35918688
http://dx.doi.org/10.1186/s12951-022-01567-7
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