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The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex

BACKGROUND: Imprinting Control Regions (ICRs) are CpG-rich sequences acquiring differential methylation in the female and male germline and maintaining it in a parental origin-specific manner in somatic cells. Despite their expected high mutation rate due to spontaneous deamination of methylated cyt...

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Detalles Bibliográficos
Autores principales: Acurzio, Basilia, Cecere, Francesco, Giaccari, Carlo, Verma, Ankit, Russo, Rosita, Valletta, Mariangela, Hay Mele, Bruno, Angelini, Claudia, Chambery, Angela, Riccio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344765/
https://www.ncbi.nlm.nih.gov/pubmed/35918739
http://dx.doi.org/10.1186/s13072-022-00462-7