ATP enhances the error-prone ribonucleotide incorporation by the SARS-CoV-2 RNA polymerase

The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or COVID-19) has caused a global pandemic. The SARS-CoV-2 RNA genome is replicated by a conserved “core” replication-transcription complex (RTC) containing an error-prone RNA-dependent RNA polymerase holoenzyme (holo-RdRp, nsp12-n...

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Detalles Bibliográficos
Autores principales: Pourfarjam, Yasin, Ma, Zhijun, Kim, In-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344795/
https://www.ncbi.nlm.nih.gov/pubmed/35947915
http://dx.doi.org/10.1016/j.bbrc.2022.07.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344795/
https://www.ncbi.nlm.nih.gov/pubmed/35947915
http://dx.doi.org/10.1016/j.bbrc.2022.07.087

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