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ATP enhances the error-prone ribonucleotide incorporation by the SARS-CoV-2 RNA polymerase
The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or COVID-19) has caused a global pandemic. The SARS-CoV-2 RNA genome is replicated by a conserved “core” replication-transcription complex (RTC) containing an error-prone RNA-dependent RNA polymerase holoenzyme (holo-RdRp, nsp12-n...
Autores principales: | Pourfarjam, Yasin, Ma, Zhijun, Kim, In-Kwon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344795/ https://www.ncbi.nlm.nih.gov/pubmed/35947915 http://dx.doi.org/10.1016/j.bbrc.2022.07.087 |
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