MC4R biased signalling and the conformational basis of biological function selections

The MC4R, a GPCR, has long been a major target for obesity treatment. As the most well‐studied melanocortin receptor subtype, the evolutionary knowledge pushes the drug development and structure–activity relationship (SAR) moving forward. The past decades have witnessed the evolution of scientists&#...

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Detalles Bibliográficos
Autores principales: Liu, Zekun, Hruby, Victor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344818/
https://www.ncbi.nlm.nih.gov/pubmed/35818295
http://dx.doi.org/10.1111/jcmm.17441

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