Lysine‐specific demethylase 1 aggravated oxidative stress and ferroptosis induced by renal ischemia and reperfusion injury through activation of TLR4/NOX4 pathway in mice

Acute kidney injury (AKI) is mainly caused by renal ischaemia reperfusion injury (IRI). Lots of evidence suggests that ferroptosis and oxidative stress play the vital role in renal IRI. However, the specific mechanism of renal IRI has not been fully elucidated. lysine‐specific demethylase 1 (LSD1) h...

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Detalles Bibliográficos
Autores principales: Feng, Ruikang, Xiong, Yufeng, Lei, Yourong, Huang, Qin, Liu, Hao, Zhao, Xiaojie, Chen, Zhiyuan, Chen, Hui, Liu, Xiuheng, Wang, Lei, Weng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344828/
https://www.ncbi.nlm.nih.gov/pubmed/35775122
http://dx.doi.org/10.1111/jcmm.17444

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