NanoSplicer: accurate identification of splice junctions using Oxford Nanopore sequencing

MOTIVATION: Long-read sequencing methods have considerable advantages for characterizing RNA isoforms. Oxford Nanopore sequencing records changes in electrical current when nucleic acid traverses through a pore. However, basecalling of this raw signal (known as a squiggle) is error prone, making it...

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Detalles Bibliográficos
Autores principales: You, Yupei, Clark, Michael B, Shim, Heejung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344838/
https://www.ncbi.nlm.nih.gov/pubmed/35639973
http://dx.doi.org/10.1093/bioinformatics/btac359

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