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Novel Alzheimer risk factor IQ motif containing protein K is abundantly expressed in the brain and is markedly increased in patients with Alzheimer’s disease

Alzheimer’s disease (AD) is complex and highly heterogeneous. Less than 10% of AD cases are early-onset (EOAD) caused by autosomal dominantly inherited mutations in amyloid precursor protein (APP), presenilin 1 (PS1), or presenilin 2 (PS2), each of which can increase Aβ generation and, thus, amyloid...

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Detalles Bibliográficos
Autores principales: Wang, Hongjie, Devadoss, Dinesh, Nair, Madhavan, Chand, Hitendra S., Lakshmana, Madepalli K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344928/
https://www.ncbi.nlm.nih.gov/pubmed/35928571
http://dx.doi.org/10.3389/fncel.2022.954071