Cargando…

Novel Alzheimer risk factor IQ motif containing protein K is abundantly expressed in the brain and is markedly increased in patients with Alzheimer’s disease

Alzheimer’s disease (AD) is complex and highly heterogeneous. Less than 10% of AD cases are early-onset (EOAD) caused by autosomal dominantly inherited mutations in amyloid precursor protein (APP), presenilin 1 (PS1), or presenilin 2 (PS2), each of which can increase Aβ generation and, thus, amyloid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Hongjie, Devadoss, Dinesh, Nair, Madhavan, Chand, Hitendra S., Lakshmana, Madepalli K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344928/ https://www.ncbi.nlm.nih.gov/pubmed/35928571 http://dx.doi.org/10.3389/fncel.2022.954071

Ejemplares similares

SARS-CoV-2 Infection in the Central and Peripheral Nervous System-Associated Morbidities and Their Potential Mechanism
por: Karuppan, Mohan Kumar Muthu, et al.
Publicado: (2021)

Transcription Factor EB Is Selectively Reduced in the Nuclear Fractions of Alzheimer's and Amyotrophic Lateral Sclerosis Brains
por: Wang, Hongjie, et al.
Publicado: (2016)

IQ Motif-Containing G (Iqcg) Is Required for Mouse Spermiogenesis
por: Harris, Tanya P., et al.
Publicado: (2013)

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine
por: Hayes, Crystal D, et al.
Publicado: (2013)

Increased Expression of LASI lncRNA Regulates the Cigarette Smoke and COPD Associated Airway Inflammation and Mucous Cell Hyperplasia
por: Manevski, Marko, et al.
Publicado: (2022)

Corrigendum: Increased expression of LASI LncRNA regulates the cigarette smoke and COPD associated airway inflammation and mucous cell hyperplasia
por: Manevski, Marko, et al.
Publicado: (2022)

Role of IQ Motif-Containing GTPase-Activating Proteins in Hepatocellular Carcinoma
por: Dai, Qingqing, et al.
Publicado: (2022)

TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits12
por: Wang, Hongjie, et al.
Publicado: (2016)

Anti-inflammatory effects of CBD in human microglial cell line infected with HIV-1
por: Yndart Arias, Adriana, et al.
Publicado: (2023)

E-cigarette synthetic cooling agent WS-23 and nicotine aerosols differentially modulate airway epithelial cell responses
por: Manevski, Marko, et al.
Publicado: (2022)

Limb body wall complex, amniotic band sequence, or new syndrome caused by mutation in IQ Motif containing K (IQCK)?
por: Kruszka, Paul, et al.
Publicado: (2015)

RanBP9 Overexpression Accelerates Loss of Pre and Postsynaptic Proteins in the APΔE9 Transgenic Mouse Brain
por: Wang, Hongjie, et al.
Publicado: (2014)

Correction: RanBP9 Overexpression Accelerates Loss of Pre and Postsynaptic Proteins in the APΔE9 Transgenic Mouse Brain
por: Wang, Hongjie, et al.
Publicado: (2019)

A Comparative Evaluation of a Novel Vaccine in APP/PS1 Mouse Models of Alzheimer's Disease
por: Carrera, Iván, et al.
Publicado: (2015)

Potential Role of Phosphoglycerol Dihydroceramide Produced by Periodontal Pathogen Porphyromonas gingivalis in the Pathogenesis of Alzheimer’s Disease
por: Yamada, Chiaki, et al.
Publicado: (2020)

Chronic Cladribine Administration Increases Amyloid Beta Peptide Generation and Plaque Burden in Mice
por: Hayes, Crystal D., et al.
Publicado: (2012)

Comprehensive analysis of the expression and prognosis for IQ motif-containing GTPase-activating proteins in hepatocellular carcinoma
por: Dai, Qingqing, et al.
Publicado: (2022)

SARS-CoV-2-induced autophagy dysregulation may cause neuronal dysfunction in COVID-19
por: Lakshmana, Madepalli K.
Publicado: (2021)

LRP1 Downregulates the Alzheimer’s β-Secretase BACE1 by Modulating Its Intraneuronal Trafficking1,2,3
por: Tanokashira, Daisuke, et al.
Publicado: (2015)

Watch the GAP: Emerging Roles for IQ Motif-Containing GTPase-Activating Proteins IQGAPs in Hepatocellular Carcinoma
por: Schmidt, Valentina A.
Publicado: (2012)

Immunomodulatory LncRNA on antisense strand of ICAM-1 augments SARS-CoV-2 infection-associated airway mucoinflammatory phenotype
por: Devadoss, Dinesh, et al.
Publicado: (2022)

Role of Non-Coding RNAs in Lung Circadian Clock Related Diseases
por: Chinnapaiyan, Srinivasan, et al.
Publicado: (2020)

The IQ Motif is Crucial for Ca(v)1.1 Function
por: Stroffekova, Katarina
Publicado: (2011)

IQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice
por: Ghaleb, Amr M., et al.
Publicado: (2015)

An ancient testis-specific IQ motif-containing H gene regulates specific transcript isoform expression during spermatogenesis
por: Navarrete-López, Paula, et al.
Publicado: (2023)

Do calmodulin binding IQ motifs have built‐in capping domains?
por: Muguruza‐Montero, Arantza, et al.
Publicado: (2021)

Depletion of IQ motif-containing GTPase activating protein 2 (IQGAP2) reduces hepatic glycogen and impairs insulin signaling
por: Sen, Anushna, et al.
Publicado: (2023)

Alzheimer’s disease: pathogenesis, diagnostics, and therapeutics
por: Tiwari, Sneham, et al.
Publicado: (2019)

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer’s Disease
por: Rajeshwari, Rajeshwari, et al.
Publicado: (2019)

The Specificity of EGF-Stimulated IQGAP1 Scaffold Towards the PI3K-Akt Pathway is Defined by the IQ3 motif
por: Chen, Mo, et al.
Publicado: (2019)

2021 marks a new era for Alzheimer's therapeutics
por: Kantarci, Kejal
Publicado: (2022)

Indoor-air purification by photoelectrochemical oxidation mitigates allergic airway responses to aerosolized cat dander in a murine model
por: Devadoss, Dinesh, et al.
Publicado: (2023)

Genetic risk for Alzheimer disease in children: Evidence from early‐life IQ and brain white‐matter microstructure
por: Vinueza‐Veloz, María Fernanda, et al.
Publicado: (2020)

Increased microRNA-34c abundance in Alzheimer's disease circulating blood plasma
por: Bhatnagar, Shephali, et al.
Publicado: (2014)

High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: Interaction with IQ motif-containing factors
por: Robinson, Tyler JW, et al.
Publicado: (2013)

RNA Interference of IQ Motif Containing GTPase-Activating Protein 3 (IQGAP3) Inhibits Cell Proliferation and Invasion in Breast Carcinoma Cells
por: Hu, Gaowu, et al.
Publicado: (2016)

Accumulation of network redundancy marks the early stage of Alzheimer's disease
por: Ghanbari, Maryam, et al.
Publicado: (2023)

Cellular stress responses and dysfunctional Mitochondrial–cellular senescence, and therapeutics in chronic respiratory diseases
por: Manevski, Marko, et al.
Publicado: (2020)

A Long Noncoding RNA Antisense to ICAM-1 is Involved in Allergic Asthma Associated Hyperreactive Response of Airway Epithelial Cells
por: Devadoss, Dinesh, et al.
Publicado: (2020)

MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies
por: Lund, Harald, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1ivpnll898qo4hm6c0pq24efi4