Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer’s Disease

Alzheimer’s disease (AD) is increasingly seen as a disease of synapses and diverse evidence has implicated the amyloid-β peptide (Aβ) in synapse damage. The molecular and cellular mechanism(s) by which Aβ and/or its precursor protein, the amyloid precursor protein (APP) can affect synapses remains u...

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Detalles Bibliográficos
Autores principales: Martinsson, Isak, Quintino, Luis, Garcia, Megg G., Konings, Sabine C., Torres-Garcia, Laura, Svanbergsson, Alexander, Stange, Oliver, England, Rebecca, Deierborg, Tomas, Li, Jia-Yi, Lundberg, Cecilia, Gouras, Gunnar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344931/
https://www.ncbi.nlm.nih.gov/pubmed/35928998
http://dx.doi.org/10.3389/fnagi.2022.946297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344931/
https://www.ncbi.nlm.nih.gov/pubmed/35928998
http://dx.doi.org/10.3389/fnagi.2022.946297

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