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Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression

AIM: To support decision‐making for early interventional radiology, this study aimed to derive and validate a novel and simple scoring system for predicting the necessity of interventional radiology therapies in trauma patients. METHODS: This retrospective study used data derived from the medical re...

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Autores principales: Yokoyama, Taro, Nakahara, Shinji, Kondo, Hiroshi, Miyake, Yasufumi, Sakamoto, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345292/
https://www.ncbi.nlm.nih.gov/pubmed/35928218
http://dx.doi.org/10.1002/ams2.774
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author Yokoyama, Taro
Nakahara, Shinji
Kondo, Hiroshi
Miyake, Yasufumi
Sakamoto, Tetsuya
author_facet Yokoyama, Taro
Nakahara, Shinji
Kondo, Hiroshi
Miyake, Yasufumi
Sakamoto, Tetsuya
author_sort Yokoyama, Taro
collection PubMed
description AIM: To support decision‐making for early interventional radiology, this study aimed to derive and validate a novel and simple scoring system for predicting the necessity of interventional radiology therapies in trauma patients. METHODS: This retrospective study used data derived from the medical records of patients with severe traumatic injuries treated at a tertiary‐level emergency institution. The score was derived from 168 patients treated between April 2015 and October 2016 and validated using data from 68 patients treated between November 2016 and July 2017. Logistic “least absolute shrinkage and selection operator (LASSO)” regression was used to select predictors. In order to compose the score, odds ratios derived from the logistic model were simplified to integer score coefficients. The score was evaluated using the area under the receiver operating characteristic curve. The best cut‐off point for the score was determined using Youden’s index, and sensitivity and specificity were calculated. RESULTS: The derived score comprised three predictors (systolic blood pressure, positive findings in abdominal ultrasound assessment, and pelvic fracture) and ranged from 0 to 30. On validation, the area under the receiver operating characteristic curve for the score was 0.86 (95% confidence interval, 0.64–1.00). The sensitivity and specificity were 80% and 89%, respectively, with a cut‐off point of 3. CONCLUSION: This simple score, requiring variables obtainable immediately after hospital arrival, could aid in facilitating early interventional radiology team activation.
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spelling pubmed-93452922022-08-03 Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression Yokoyama, Taro Nakahara, Shinji Kondo, Hiroshi Miyake, Yasufumi Sakamoto, Tetsuya Acute Med Surg Original Articles AIM: To support decision‐making for early interventional radiology, this study aimed to derive and validate a novel and simple scoring system for predicting the necessity of interventional radiology therapies in trauma patients. METHODS: This retrospective study used data derived from the medical records of patients with severe traumatic injuries treated at a tertiary‐level emergency institution. The score was derived from 168 patients treated between April 2015 and October 2016 and validated using data from 68 patients treated between November 2016 and July 2017. Logistic “least absolute shrinkage and selection operator (LASSO)” regression was used to select predictors. In order to compose the score, odds ratios derived from the logistic model were simplified to integer score coefficients. The score was evaluated using the area under the receiver operating characteristic curve. The best cut‐off point for the score was determined using Youden’s index, and sensitivity and specificity were calculated. RESULTS: The derived score comprised three predictors (systolic blood pressure, positive findings in abdominal ultrasound assessment, and pelvic fracture) and ranged from 0 to 30. On validation, the area under the receiver operating characteristic curve for the score was 0.86 (95% confidence interval, 0.64–1.00). The sensitivity and specificity were 80% and 89%, respectively, with a cut‐off point of 3. CONCLUSION: This simple score, requiring variables obtainable immediately after hospital arrival, could aid in facilitating early interventional radiology team activation. John Wiley and Sons Inc. 2022-08-02 /pmc/articles/PMC9345292/ /pubmed/35928218 http://dx.doi.org/10.1002/ams2.774 Text en © 2022 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Yokoyama, Taro
Nakahara, Shinji
Kondo, Hiroshi
Miyake, Yasufumi
Sakamoto, Tetsuya
Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression
title Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression
title_full Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression
title_fullStr Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression
title_full_unstemmed Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression
title_short Novel score for predicting early emergency endovascular therapy in trauma care using logistic LASSO regression
title_sort novel score for predicting early emergency endovascular therapy in trauma care using logistic lasso regression
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345292/
https://www.ncbi.nlm.nih.gov/pubmed/35928218
http://dx.doi.org/10.1002/ams2.774
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