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Optimisation of anti-interleukin-6 therapy: Precision medicine through mathematical modelling

BACKGROUND: Dysregulated interleukin (IL)-6 production can be characterised by the levels present, the kinetics of its rise and its inappropriate location. Rapid, excessive IL-6 production can exacerbate tissue damage in vital organs. In this situation, therapy with an anti-IL-6 or anti-IL-6 recepto...

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Detalles Bibliográficos
Autores principales:	Rossi, Jean-François, Chiang, Hao-Chun, Lu, Zhao-Yang, Levon, Kalle, van Rhee, Frits, Kanhai, Karan, Fajgenbaum, David C., Klein, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345304/ https://www.ncbi.nlm.nih.gov/pubmed/35928820 http://dx.doi.org/10.3389/fimmu.2022.919489

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