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Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer’s disease

In Alzheimer’s disease, synapse loss causes memory and cognitive impairment. However, the mechanisms underlying synaptic degeneration in Alzheimer’s disease are not well understood. In the hippocampus, alterations in the level of cysteine string protein alpha, a molecular co-chaperone at the pre-syn...

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Detalles Bibliográficos
Autores principales: Rupawala, Huzefa, Shah, Keshvi, Davies, Caitlin, Rose, Jamie, Colom-Cadena, Marti, Peng, Xianhui, Granat, Lucy, Aljuhani, Manal, Mizuno, Keiko, Troakes, Claire, Perez-Nievas, Beatriz Gomez, Morgan, Alan, So, Po-Wah, Hortobagyi, Tibor, Spires-Jones, Tara L, Noble, Wendy, Giese, Karl Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345313/
https://www.ncbi.nlm.nih.gov/pubmed/35928052
http://dx.doi.org/10.1093/braincomms/fcac192