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Cysteine string protein alpha accumulates with early pre-synaptic dysfunction in Alzheimer’s disease
In Alzheimer’s disease, synapse loss causes memory and cognitive impairment. However, the mechanisms underlying synaptic degeneration in Alzheimer’s disease are not well understood. In the hippocampus, alterations in the level of cysteine string protein alpha, a molecular co-chaperone at the pre-syn...
Autores principales: | Rupawala, Huzefa, Shah, Keshvi, Davies, Caitlin, Rose, Jamie, Colom-Cadena, Marti, Peng, Xianhui, Granat, Lucy, Aljuhani, Manal, Mizuno, Keiko, Troakes, Claire, Perez-Nievas, Beatriz Gomez, Morgan, Alan, So, Po-Wah, Hortobagyi, Tibor, Spires-Jones, Tara L, Noble, Wendy, Giese, Karl Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345313/ https://www.ncbi.nlm.nih.gov/pubmed/35928052 http://dx.doi.org/10.1093/braincomms/fcac192 |
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