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Decitabine attenuates ischemic stroke by reducing astrocytes proliferation in rats

DNA methylation regulates epigenetic gene expression in ischemic stroke. Decitabine attenuates ischemic stroke by inhibiting DNA methylation. However, the underlying mechanism of this effect is not known. A model of ischemic stroke in Sprague-Dawley rats was induced through middle cerebral artery oc...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Li, Dan, Zhao, Haihua, Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345475/
https://www.ncbi.nlm.nih.gov/pubmed/35917376
http://dx.doi.org/10.1371/journal.pone.0272482

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