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Iron controls T helper cell pathogenicity by promoting glucose metabolism in autoimmune myopathy

BACKGROUND: T helper cells in patients with autoimmune disease of idiopathic inflammatory myopathies (IIM) are characterized with the proinflammatory phenotypes. The underlying mechanisms remain unknown. METHODS: RNA sequencing was performed for differential expression genes. Gene expression in CD4(...

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Detalles Bibliográficos
Autores principales: Lai, Yimei, Zhao, Siyuan, Chen, Binfeng, Huang, Yuefang, Guo, Chaohuan, Li, Mengyuan, Ye, Baokui, Wang, Shuyi, Zhang, Hui, Yang, Niansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345506/
https://www.ncbi.nlm.nih.gov/pubmed/35917405
http://dx.doi.org/10.1002/ctm2.999