Cargando…

Salvianolic acid B attenuates membranous nephropathy by activating renal autophagy via microRNA-145-5p/phosphatidylinositol 3-kinase/AKT pathway

The abnormal proliferation and inflammatory response of the mesangial cells play a crucial role in the progression of membranous nephropathy (MN). Herein, this study aimed to investigate the therapeutic effect of Salvianolic acid B (SalB) on MN-induced mesangial abnormalities and its underlying mech...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Junqi, Hu, Qinghong, Luo, Yini, Luo, Lina, Lin, Hua, Chen, Dandan, Xu, Yuan, Liu, Bihao, He, Yu, Liang, Chunling, Liu, Yaoyu, Zhou, Jiuyao, Wu, Junbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345616/ https://www.ncbi.nlm.nih.gov/pubmed/35723058 http://dx.doi.org/10.1080/21655979.2022.2083822

Ejemplares similares

Zhen-Wu-Tang Induced Mitophagy to Protect Mitochondrial Function in Chronic Glomerulonephritis via PI3K/AKT/mTOR and AMPK Pathways
por: Liu, Bihao, et al.
Publicado: (2021)

The landscape of immune cell infiltration in the glomerulus of diabetic nephropathy: evidence based on bioinformatics
por: ZHOU, Wei, et al.
Publicado: (2022)

Paeoniflorin Inhibits Mesangial Cell Proliferation and Inflammatory Response in Rats With Mesangial Proliferative Glomerulonephritis Through PI3K/AKT/GSK-3β Pathway
por: Liu, Bihao, et al.
Publicado: (2019)

Zhen-Wu-Tang Protects IgA Nephropathy in Rats by Regulating Exosomes to Inhibit NF-κB/NLRP3 Pathway
por: Li, Honglian, et al.
Publicado: (2020)

Integrated Fecal Microbiome and Serum Metabolomics Analysis Reveals Abnormal Changes in Rats with Immunoglobulin A Nephropathy and the Intervention Effect of Zhen Wu Tang
por: Li, Jicheng, et al.
Publicado: (2021)

Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro
por: Wang, Chunhua, et al.
Publicado: (2018)

Salvianolic acid A as a multifunctional agent ameliorates doxorubicin-induced nephropathy in rats
por: Fan, Hua-Ying, et al.
Publicado: (2015)

The Effects of Salvianolate Combined With Western Medicine on Diabetic Nephropathy: A Systematic Review and Meta-Analysis
por: Shen, Yuehong, et al.
Publicado: (2020)

Salvianolic acid B promotes angiogenesis and inhibits cardiomyocyte apoptosis by regulating autophagy in myocardial ischemia
por: Chen, Qi, et al.
Publicado: (2023)

Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway
por: Lin, Pinglan, et al.
Publicado: (2022)

Wogonin Increases Cisplatin Sensitivity in Ovarian Cancer Cells Through Inhibition of the Phosphatidylinositol 3-Kinase (PI3K)/Akt Pathway
por: Xing, Feng, et al.
Publicado: (2019)

Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway
por: Ye, Tingting, et al.
Publicado: (2022)

Salvianolate injection for hypertensive nephropathy patients who were using valsartan: A systematic review and meta-analysis
por: Xu, Qiyao, et al.
Publicado: (2023)

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
por: Wu, Jia-Zhen, et al.
Publicado: (2019)

Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy
por: Lin, Jinti, et al.
Publicado: (2018)

Salvianolic Acid B Inhibits Hydrogen Peroxide-Induced Endothelial Cell Apoptosis through Regulating PI3K/Akt Signaling
por: Liu, Chen-Li, et al.
Publicado: (2007)

Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage
por: Xiao, Zhun, et al.
Publicado: (2020)

CircRNA_0001449 disturbs phosphatidylinositol homeostasis and AKT activity by enhancing Osbpl5 translation in transient cerebral ischemia
por: Shang, Fei-Fei, et al.
Publicado: (2020)

Autophagy Restricts Proliferation Driven By Oncogenic Phosphatidylinositol 3-Kinase in Three-Dimensional Culture
por: Chen, Nan, et al.
Publicado: (2012)

Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells
por: Xiang, Jie, et al.
Publicado: (2022)

Cardiovascular Effects of Salvianolic Acid B
por: Wang, Jie, et al.
Publicado: (2013)

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro
por: Dai, Jian-Ping, et al.
Publicado: (2015)

The long non-coding RNA SNHG12 promotes gastric cancer by activating the phosphatidylinositol 3-kinase/AKT pathway
por: Zhang, Rui, et al.
Publicado: (2019)

miR‐145 inhibits the proliferation and migration of vascular smooth muscle cells by regulating autophagy
por: Wang, Weirong, et al.
Publicado: (2020)

Salvianolic Acid B Attenuates Rat Hepatic Fibrosis via Downregulating Angiotensin II Signaling
por: Li, Shu, et al.
Publicado: (2012)

Participation of the phosphatidylinositol 3-kinase/Akt pathway in Junín virus replication in vitro
por: Linero, F.N., et al.
Publicado: (2009)

Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells
por: Jing, Zhao, et al.
Publicado: (2016)

Perspectives for Forkhead box transcription factors in diabetic cardiomyopathy: Their therapeutic potential and possible effects of salvianolic acids
por: Han, Ronghui, et al.
Publicado: (2022)

Autophagy and its therapeutic potential in diabetic nephropathy
por: Han, Yu-Peng, et al.
Publicado: (2023)

Synthesis of Pelorol and Its Analogs and Their Inhibitory Effects on Phosphatidylinositol 3-Kinase
por: Luo, Yongjie, et al.
Publicado: (2016)

Current Progress of Research on Neurodegenerative Diseases of Salvianolic Acid B
por: Zhao, Rui, et al.
Publicado: (2019)

Salvianolic acid A targeting the transgelin-actin complex to enhance vasoconstriction
por: Zhong, Weilong, et al.
Publicado: (2018)

Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity
por: Araki, Yasuhiro, et al.
Publicado: (2013)

Cardio-Protection of Salvianolic Acid B through Inhibition of Apoptosis Network
por: Xu, Lingling, et al.
Publicado: (2011)

Salvianolic acid B protects hepatocytes from H(2)O(2) injury by stabilizing the lysosomal membrane
por: Yan, Xiao-Feng, et al.
Publicado: (2017)

Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin
por: Liu, Yunxia, et al.
Publicado: (2017)

m(6)A-induced lncRNA MALAT1 aggravates renal fibrogenesis in obstructive nephropathy through the miR-145/FAK pathway
por: Liu, Peihua, et al.
Publicado: (2020)

Activated Phosphatidylinositol 3-Kinase and Akt Kinase Promote Survival of Superior Cervical Neurons
por: Philpott, Karen L., et al.
Publicado: (1997)

Prognostic implications of phosphatidylinositol 3-kinase/AKT signaling pathway activation in gastric carcinomas
por: Chiappini, Paula Blandina Ola, et al.
Publicado: (2016)

Salvianolate Protects Hepatocytes from Oxidative Stress by Attenuating Mitochondrial Injury
por: Zhao, Qiang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_l7g5tl8b4sq05t2am65d980sj7