Cargando…

Wumei Pill Ameliorates AOM/DSS-Induced Colitis-Associated Colon Cancer through Inhibition of Inflammation and Oxidative Stress by Regulating S-Adenosylhomocysteine Hydrolase- (AHCY-) Mediated Hedgehog Signaling in Mice

Wumei Pill (WMP) is a traditional Chinese herbal formulation and widely used to treat digestive system diseases in clinical. S-Adenosylhomocysteine hydrolase (AHCY) can catalyze the hydrolysis of S-adenosylhomocysteine to adenosine and homocysteine in living organisms, and its abnormal expression is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jue, Ding, Kang, Wang, Yuhang, Yan, Tingdong, Xu, Yun, Deng, Zirong, Lin, Weiling, Zhang, Libei, Zhu, Weizhong, Zhao, Rui, Zhou, Yuhang, Liu, Zhaoguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345734/ https://www.ncbi.nlm.nih.gov/pubmed/35927991 http://dx.doi.org/10.1155/2022/4061713

Ejemplares similares

Abnormal Hypermethylation at Imprinting Control Regions in Patients with S-Adenosylhomocysteine Hydrolase (AHCY) Deficiency
por: Motzek, Antje, et al.
Publicado: (2016)

Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology
por: Huang, Jinke, et al.
Publicado: (2021)

Inhibition of Ribosomal RNA Processing 15 Homolog (RRP15) Suppressed Tumor Growth, Invasion and Epithelial to Mesenchymal Transition (EMT) of Colon Cancer
por: Deng, Zirong, et al.
Publicado: (2023)

Emodin Inhibits Inflammation, Carcinogenesis, and Cancer Progression in the AOM/DSS Model of Colitis-Associated Intestinal Tumorigenesis
por: Zhang, Yunsha, et al.
Publicado: (2021)

S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice
por: Lee, Hyung-Ok, et al.
Publicado: (2018)

Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms
por: Wan, Yuxiang, et al.
Publicado: (2019)

Regulation of homocysteine metabolism by Mycobacterium tuberculosis S-adenosylhomocysteine hydrolase
por: Singhal, Anshika, et al.
Publicado: (2013)

The biochemical profile and dietary management in S-adenosylhomocysteine hydrolase deficiency
por: Huang, Yue, et al.
Publicado: (2022)

Protocol for colitis-associated colorectal cancer murine model induced by AOM and DSS
por: Sun, Wenbo, et al.
Publicado: (2023)

Supplementation with High or Low Iron Reduces Colitis Severity in an AOM/DSS Mouse Model
por: Moon, Seonghwan, et al.
Publicado: (2022)

Dietary Selenium Deficiency Exacerbates DSS-Induced Epithelial Injury and AOM/DSS-Induced Tumorigenesis
por: Barrett, Caitlyn W., et al.
Publicado: (2013)

Flavonoids Extracted from Licorice Prevents Colitis-Associated Carcinogenesis in AOM/DSS Mouse Model
por: Huo, Xiaowei, et al.
Publicado: (2016)

Ang1 and Ang4 differentially affect colitis and carcinogenesis in an AOM-DSS mouse model
por: Hu, Alexander, et al.
Publicado: (2023)

Functional and Pathological Roles of AHCY
por: Vizán, Pedro, et al.
Publicado: (2021)

Enterotoxigenic Bacteroides fragilis infection exacerbates tumorigenesis in AOM/DSS mouse model
por: Hwang, Soonjae, et al.
Publicado: (2020)

Zerumbone Restores Gut Microbiota Composition in ETBF Colonized AOM/DSS Mice
por: Cho, Hye-Won, et al.
Publicado: (2020)

Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy
por: Wang, Ying, et al.
Publicado: (2022)

Effects of S-Adenosylhomocysteine Hydrolase Downregulation on Wnt Signaling Pathway in SW480 Cells
por: Pavičić, Ivana, et al.
Publicado: (2023)

Clinical effect of wumei bolus on ulcerative colitis: A meta-analysis
por: Chen, Zepeng, et al.
Publicado: (2023)

Murine models of colorectal cancer: the azoxymethane (AOM)/dextran sulfate sodium (DSS) model of colitis-associated cancer
por: Dzhalilova, Dzhuliia, et al.
Publicado: (2023)

Helicobacter pylori infection reduces TAMs infiltration in a mouse model of AOM/DSS induced colitis-associated cancer
por: Li, Luo-na, et al.
Publicado: (2020)

The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies
por: Robertis, Mariangela De, et al.
Publicado: (2011)

Metabonomic Variation of Exopolysaccharide from Rhizopus nigricans on AOM/DSS-Induced Colorectal Cancer in Mice
por: Lu, Yan, et al.
Publicado: (2019)

Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors
por: Hunt, Jenna Elizabeth, et al.
Publicado: (2021)

Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice
por: Wu, Huixia, et al.
Publicado: (2023)

H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase
por: Zhou, Jichun, et al.
Publicado: (2015)

Betaine Supplementation Attenuates S-Adenosylhomocysteine Hydrolase-Deficiency-Accelerated Atherosclerosis in Apolipoprotein E-Deficient Mice
por: Dai, Xin, et al.
Publicado: (2022)

Effect of vitamin C on azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colitis-associated early colon cancer in mice
por: Jeon, Hee-Jin, et al.
Publicado: (2018)

Inhibitory Effect of Dietary Defatted Rice Bran in an AOM/DSS-Induced Colitis-Associated Colorectal Cancer Experimental Animal Model
por: Tajasuwan, Laleewan, et al.
Publicado: (2022)

Effect of Angelica sinensis Root Extract on Cancer Prevention in Different Stages of an AOM/DSS Mouse Model
por: Zhao, Bochen, et al.
Publicado: (2017)

Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice
por: Lin, Rui, et al.
Publicado: (2020)

Transcriptomic and Proteomic Study on the High-Fat Diet Combined With AOM/DSS-Induced Adenomatous Polyps in Mice
por: Guo, Cui, et al.
Publicado: (2021)

Safflower Polysaccharide Inhibits AOM/DSS-Induced Mice Colorectal Cancer Through the Regulation of Macrophage Polarization
por: Wang, Qun, et al.
Publicado: (2021)

Tanshinone IIA attenuates AOM/DSS-induced colorectal tumorigenesis in mice via inhibition of intestinal inflammation
por: Liu, Lijie, et al.
Publicado: (2021)

Chemopreventive Effect of Cooked Chickpea on Colon Carcinogenesis Evolution in AOM/DSS-Induced Balb/c Mice
por: Cid-Gallegos, María Stephanie, et al.
Publicado: (2023)

Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes
por: Aury-Landas, Juliette, et al.
Publicado: (2017)

Case Report: Advanced Skeletal Muscle Imaging in S-Adenosylhomocysteine Hydrolase Deficiency and Further Insight Into Muscle Pathology
por: Petković Ramadža, Danijela, et al.
Publicado: (2022)

Role of Dietary Defatted Rice Bran in the Modulation of Gut Microbiota in AOM/DSS-Induced Colitis-Associated Colorectal Cancer Rat Model
por: Tajasuwan, Laleewan, et al.
Publicado: (2023)

Induction of colorectal carcinogenesis in the C57BL/6J and A/J mouse strains with a reduced DSS dose in the AOM/DSS model
por: Arnesen, Henriette, et al.
Publicado: (2021)

Synergistic Effect of Huangqin Decoction Combined Treatment With Radix Actinidiae chinensis on DSS and AOM-Induced Colorectal Cancer
por: Huang, Jianbo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q2ihtlafuh9dgfcugjn4o575a3