Dopamine D2 Receptor Signaling Attenuates Acinar Cell Necroptosis in Acute Pancreatitis through the Cathepsin B/TFAM/ROS Pathway

Acute pancreatitis (AP) is an inflammatory disease that is associated with trypsinogen activation, mitochondrial dysfunction, cell death, and inflammation. Dopamine D2 receptor (DRD2) plays an essential role in alleviating AP, while it is unclear whether it is involved in regulating acinar cell necr...

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Detalles Bibliográficos
Autores principales: Wu, Zengkai, Han, Xiao, Bao, Jingpiao, Li, Bin, Shen, Jie, Song, Pengli, Peng, Qi, Wang, Xingpeng, Hu, Guoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345736/
https://www.ncbi.nlm.nih.gov/pubmed/35927992
http://dx.doi.org/10.1155/2022/4499219

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