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Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma
The outcomes of metastatic and nonresponder pediatric osteosarcoma patients are very poor and have not improved in the last 30 years. These tumors harbor a highly immunosuppressive environment, making existing immunotherapies ineffective. Here, we evaluated the use of Semliki Forest virus (SFV) vect...
Autores principales: | Herrador-Cañete, Guillermo, Zalacain, Marta, Labiano, Sara, Laspidea, Virginia, Puigdelloses, Montserrat, Marrodan, Lucía, Garcia-Moure, Marc, Gonzalez-Huarriz, Marisol, Marco-Sanz, Javier, Ausejo-Mauleon, Iker, de la Nava, Daniel, Hernández-Osuna, Reyes, Martínez-García, Javier, Silva-Pilipich, Noelia, Gurucega, Elisabeth, Patiño-García, Ana, Hernández-Alcoceba, Rubén, Smerdou, Cristian, Alonso, Marta M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345771/ https://www.ncbi.nlm.nih.gov/pubmed/35949950 http://dx.doi.org/10.1016/j.omto.2022.07.004 |
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