Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis?

Since most pharmacological treatments in case of esophageal food impaction (EFI) are unsuccessful, an endoscopy is usually required to resolve EFI. We present the first results of a budesonide orodispersible tablet (BOT) as a medical treatment option before endoscopy. We evaluated all patients with...

Descripción completa

Detalles Bibliográficos
Autores principales: Schreiner, Philipp, Greuter, Thomas, Tatu, Aurora, Keller, Dagmar I., Straumann, Alex, Biedermann, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345796/
https://www.ncbi.nlm.nih.gov/pubmed/34398319
http://dx.doi.org/10.1007/s00455-021-10354-9
_version_ 1784761510823723008
author Schreiner, Philipp
Greuter, Thomas
Tatu, Aurora
Keller, Dagmar I.
Straumann, Alex
Biedermann, Luc
author_facet Schreiner, Philipp
Greuter, Thomas
Tatu, Aurora
Keller, Dagmar I.
Straumann, Alex
Biedermann, Luc
author_sort Schreiner, Philipp
collection PubMed
description Since most pharmacological treatments in case of esophageal food impaction (EFI) are unsuccessful, an endoscopy is usually required to resolve EFI. We present the first results of a budesonide orodispersible tablet (BOT) as a medical treatment option before endoscopy. We evaluated all patients with a suspected EFI to receive BOT before emergent endoscopy at a tertiary hospital between March 2019 and June 2020. A total of eight patients received BOT before endoscopy. Mean age was 50.1 years and 87.5% were male. In 38% (3/8) of patients the EFI resolved without endoscopic intervention. No adverse events occurred. After endoscopy, a diagnosis of EoE was established in 75%. This case series demonstrate the potential of BOT as medical rescue therapy in case of EFI.
format Online
Article
Text
id pubmed-9345796
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-93457962022-08-04 Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis? Schreiner, Philipp Greuter, Thomas Tatu, Aurora Keller, Dagmar I. Straumann, Alex Biedermann, Luc Dysphagia Original Article Since most pharmacological treatments in case of esophageal food impaction (EFI) are unsuccessful, an endoscopy is usually required to resolve EFI. We present the first results of a budesonide orodispersible tablet (BOT) as a medical treatment option before endoscopy. We evaluated all patients with a suspected EFI to receive BOT before emergent endoscopy at a tertiary hospital between March 2019 and June 2020. A total of eight patients received BOT before endoscopy. Mean age was 50.1 years and 87.5% were male. In 38% (3/8) of patients the EFI resolved without endoscopic intervention. No adverse events occurred. After endoscopy, a diagnosis of EoE was established in 75%. This case series demonstrate the potential of BOT as medical rescue therapy in case of EFI. Springer US 2021-08-16 2022 /pmc/articles/PMC9345796/ /pubmed/34398319 http://dx.doi.org/10.1007/s00455-021-10354-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Schreiner, Philipp
Greuter, Thomas
Tatu, Aurora
Keller, Dagmar I.
Straumann, Alex
Biedermann, Luc
Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis?
title Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis?
title_full Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis?
title_fullStr Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis?
title_full_unstemmed Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis?
title_short Is There a Role for Topical Swallowed Steroids upon Emergency Room Admission for Suspected Food Bolus Obstruction in Eosinophilic Esophagitis?
title_sort is there a role for topical swallowed steroids upon emergency room admission for suspected food bolus obstruction in eosinophilic esophagitis?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345796/
https://www.ncbi.nlm.nih.gov/pubmed/34398319
http://dx.doi.org/10.1007/s00455-021-10354-9
work_keys_str_mv AT schreinerphilipp istherearolefortopicalswallowedsteroidsuponemergencyroomadmissionforsuspectedfoodbolusobstructionineosinophilicesophagitis
AT greuterthomas istherearolefortopicalswallowedsteroidsuponemergencyroomadmissionforsuspectedfoodbolusobstructionineosinophilicesophagitis
AT tatuaurora istherearolefortopicalswallowedsteroidsuponemergencyroomadmissionforsuspectedfoodbolusobstructionineosinophilicesophagitis
AT kellerdagmari istherearolefortopicalswallowedsteroidsuponemergencyroomadmissionforsuspectedfoodbolusobstructionineosinophilicesophagitis
AT straumannalex istherearolefortopicalswallowedsteroidsuponemergencyroomadmissionforsuspectedfoodbolusobstructionineosinophilicesophagitis
AT biedermannluc istherearolefortopicalswallowedsteroidsuponemergencyroomadmissionforsuspectedfoodbolusobstructionineosinophilicesophagitis

Ejemplares similares