Human-specific gene CT47 blocks PRMT5 degradation to lead to meiosis arrest

Exploring the functions of human-specific genes (HSGs) is challenging due to the lack of a tractable genetic model system. Testosterone is essential for maintaining human spermatogenesis and fertility, but the underlying mechanism is unclear. Here, we identified Cancer/Testis Antigen gene family 47...

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Detalles Bibliográficos
Autores principales: Li, Chao, Feng, Yuming, Fu, Zhenxin, Deng, Junjie, Gu, Yue, Wang, Hanben, Wu, Xin, Huang, Zhengyun, Zhu, Yichen, Liu, Zhiwei, Huang, Moli, Wang, Tao, Hu, Shijun, Yao, Bing, Zeng, Yizhun, Zhou, Chengji J., Brown, Steve D. M., Liu, Yi, Vidal-Puig, Antonio, Dong, Yingying, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345867/
https://www.ncbi.nlm.nih.gov/pubmed/35918318
http://dx.doi.org/10.1038/s41420-022-01139-6

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