Cargando…

Structure and mechanism of membrane transporters

Membrane transporters are an important group of proteins in physiology and disease. Their functions make them common drug targets, but their location in the lipid bilayers poses a tremendous challenge to researchers. The current stage of development of structural biology, in addition to new research...

Descripción completa

Detalles Bibliográficos
Autor principal: Guan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345868/
https://www.ncbi.nlm.nih.gov/pubmed/35918457
http://dx.doi.org/10.1038/s41598-022-17524-1
_version_ 1784761526342647808
author Guan, Lan
author_facet Guan, Lan
author_sort Guan, Lan
collection PubMed
description Membrane transporters are an important group of proteins in physiology and disease. Their functions make them common drug targets, but their location in the lipid bilayers poses a tremendous challenge to researchers. The current stage of development of structural biology, in addition to new research tools, has largely facilitated the acquisition of knowledge about transporters and mechanisms. This Collection presents recent studies, covering bioenergetics, structure and functional characterization of various transporters, lipids-protein interactions, and novel research tool development.
format Online
Article
Text
id pubmed-9345868
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-93458682022-08-04 Structure and mechanism of membrane transporters Guan, Lan Sci Rep Editorial Membrane transporters are an important group of proteins in physiology and disease. Their functions make them common drug targets, but their location in the lipid bilayers poses a tremendous challenge to researchers. The current stage of development of structural biology, in addition to new research tools, has largely facilitated the acquisition of knowledge about transporters and mechanisms. This Collection presents recent studies, covering bioenergetics, structure and functional characterization of various transporters, lipids-protein interactions, and novel research tool development. Nature Publishing Group UK 2022-08-02 /pmc/articles/PMC9345868/ /pubmed/35918457 http://dx.doi.org/10.1038/s41598-022-17524-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Editorial
Guan, Lan
Structure and mechanism of membrane transporters
title Structure and mechanism of membrane transporters
title_full Structure and mechanism of membrane transporters
title_fullStr Structure and mechanism of membrane transporters
title_full_unstemmed Structure and mechanism of membrane transporters
title_short Structure and mechanism of membrane transporters
title_sort structure and mechanism of membrane transporters
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345868/
https://www.ncbi.nlm.nih.gov/pubmed/35918457
http://dx.doi.org/10.1038/s41598-022-17524-1
work_keys_str_mv AT guanlan structureandmechanismofmembranetransporters