Cargando…

Modifying the yeast very long chain fatty acid biosynthetic machinery by the expression of plant 3-ketoacyl CoA synthase isozymes

Eukaryotes express a multi-component fatty acid elongase to produce very long chain fatty acids (VLCFAs), which are building blocks of diverse lipids. Elongation is achieved by cyclical iteration of four reactions, the first of which generates a new carbon–carbon bond, elongating the acyl-chain. Thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stenback, Kenna E., Flyckt, Kayla S., Hoang, Trang, Campbell, Alexis A., Nikolau, Basil J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346008/ https://www.ncbi.nlm.nih.gov/pubmed/35918413 http://dx.doi.org/10.1038/s41598-022-17080-8

Ejemplares similares

A single-cell platform for reconstituting and characterizing fatty acid elongase component enzymes
por: Campbell, Alexis A., et al.
Publicado: (2019)

Overexpression of β-Ketoacyl-CoA Synthase From Vitis vinifera L. Improves Salt Tolerance in Arabidopsis thaliana
por: Yang, Zhen, et al.
Publicado: (2020)

Gating mechanism of elongating β-ketoacyl-ACP synthases
por: Mindrebo, Jeffrey T., et al.
Publicado: (2020)

Evolution and molecular basis of substrate specificity in a 3-ketoacyl-CoA synthase gene cluster from Populus trichocarpa
por: Chen, Jeff Y., et al.
Publicado: (2022)

Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases
por: Brown, Alistair K., et al.
Publicado: (2009)

BrWAX3, Encoding a β-ketoacyl-CoA Synthase, Plays an Essential Role in Cuticular Wax Biosynthesis in Chinese Cabbage
por: Yang, Shuangjuan, et al.
Publicado: (2022)

Genome-wide identification and expression analysis of 3-ketoacyl-CoA synthase gene family in rice (Oryza sativa L.) under cadmium stress
por: Yang, Lingwei, et al.
Publicado: (2023)

Overexpression of β-Ketoacyl CoA Synthase 2B.1 from Chenopodium quinoa Promotes Suberin Monomers’ Production and Salt Tolerance in Arabidopsis thaliana
por: Tariq, Faheem, et al.
Publicado: (2022)

Inhibitory Investigations of Acyl-CoA Derivatives against Human Lipoxygenase Isozymes
por: Tran, Michelle, et al.
Publicado: (2023)

Enhancing oil production in Arabidopsis through expression of a ketoacyl-ACP synthase domain of the PUFA synthase from Thraustochytrium
por: Xie, Xi, et al.
Publicado: (2019)

Molecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genes
por: Chevillard, Grégory, et al.
Publicado: (2004)

Kinetic, Structural, and Mutational Analysis of Acyl-CoA Carboxylase From Thermobifida fusca YX
por: Shivaiah, Kiran-Kumar, et al.
Publicado: (2021)

Genome mining of cyclodipeptide synthases unravels unusual tRNA-dependent diketopiperazine-terpene biosynthetic machinery
por: Yao, Tingting, et al.
Publicado: (2018)

Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation
por: Sofeo, Naazneen, et al.
Publicado: (2023)

Minor Isozymes Tailor Yeast Metabolism to Carbon Availability
por: Bradley, Patrick H., et al.
Publicado: (2019)

Synthesis of Potent Inhibitors of β-Ketoacyl-Acyl Carrier Protein Synthase III as Potential Antimicrobial Agents
por: Liu, Yan, et al.
Publicado: (2012)

DNA Markers to Discriminate Cannabis sativa L. ‘Cheungsam' with Low Tetrahydrocannabinol (THC) Content from Other South Korea Cultivars Based on the Nucleotide Sequences of Tetrahydrocannabinolic Acid Synthase and Putative 3-Ketoacyl-CoA Synthase Genes
por: Doh, Eui Jeong, et al.
Publicado: (2019)

Knockout of the two evolutionarily conserved peroxisomal 3-ketoacyl-CoA thiolases in Arabidopsis recapitulates the abnormal inflorescence meristem 1 phenotype
por: Wiszniewski, Andrew A. G., et al.
Publicado: (2014)

Shewanella oneidensis FabB: A β-ketoacyl-ACP Synthase That Works with C16:1-ACP
por: Luo, Qixia, et al.
Publicado: (2016)

Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis
por: Nanson, Jeffrey D., et al.
Publicado: (2015)

Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH)
por: Shang, Ruofeng, et al.
Publicado: (2015)

Structural Insight of KSIII (β-Ketoacyl-ACP Synthase)-like Acyltransferase ChlB3 in the Biosynthesis of Chlorothricin
por: Saeed, Asad Ullah, et al.
Publicado: (2022)

Composition and biosynthetic machinery of the Blumeria graminis f. sp. hordei conidia cell wall
por: Pham, Trang A.T., et al.
Publicado: (2019)

Studies on the synthesis and stability of α-ketoacyl peptides
por: Sajapin, Johann, et al.
Publicado: (2020)

Two Modes of Regulation of the Fatty Acid Elongase ELOVL6 by the 3-Ketoacyl-CoA Reductase KAR in the Fatty Acid Elongation Cycle
por: Naganuma, Tatsuro, et al.
Publicado: (2014)

Altered Renal Expression of Nitric Oxide Synthase Isozymes in Spontaneously Hypertensive Rats
por: Kim, Soo-Wan, et al.
Publicado: (1999)

Enediyne Polyketide Synthases Stereoselectively Reduce the β-Ketoacyl Intermediates to β-d-Hydroxyacyl Intermediates in Enediyne Core Biosynthesis
por: Ge, Hui-Ming, et al.
Publicado: (2014)

Tapetal 3-Ketoacyl-Coenzyme A Synthases Are Involved in Pollen Coat Lipid Accumulation for Pollen-Stigma Interaction in Arabidopsis
por: Zhang, Zaibao, et al.
Publicado: (2021)

Regulation of the CoA Biosynthetic Complex Assembly in Mammalian Cells
por: Baković, Jovana, et al.
Publicado: (2021)

α-proteobacteria synthesize biotin precursor pimeloyl-ACP using BioZ 3-ketoacyl-ACP synthase and lysine catabolism
por: Hu, Yuanyuan, et al.
Publicado: (2020)

Improved chemical and isotopic labeling of biomembranes in Bacillus subtilis by leveraging CRISPRi inhibition of beta-ketoacyl-ACP synthase (fabF)
por: Nickels, Jonathan D., et al.
Publicado: (2022)

Crystal Structures of Two Isozymes of Citrate Synthase from Sulfolobus tokodaii Strain 7
por: Murakami, Midori, et al.
Publicado: (2016)

Two Chalcone Synthase Isozymes Participate Redundantly in UV-Induced Sakuranetin Synthesis in Rice
por: Park, Hye Lin, et al.
Publicado: (2020)

Conservation of two lineages of peroxisomal (Type I) 3-ketoacyl-CoA thiolases in land plants, specialization of the genes in Brassicaceae, and characterization of their expression in Arabidopsis thaliana
por: Wiszniewski, Andrew A. G., et al.
Publicado: (2012)

Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration
por: Tsachaki, Maria, et al.
Publicado: (2019)

Peroxisomal KAT2 (3-ketoacyl-CoA thiolase 2) gene has a key role in gingerol biosynthesis in ginger (Zingiber officinale Rosc.)
por: Sreeja, S., et al.
Publicado: (2023)

The Intracellular Localization of the Vanillin Biosynthetic Machinery in Pods of Vanilla planifolia
por: Gallage, Nethaji J, et al.
Publicado: (2018)

Very long-/ and long Chain-3-Hydroxy Acyl CoA Dehydrogenase Deficiency correlates with deregulation of the mitochondrial fusion/fission machinery
por: Hagenbuchner, Judith, et al.
Publicado: (2018)

β-Ketoacyl-acyl Carrier Protein Synthase I (KASI) Plays Crucial Roles in the Plant Growth and Fatty Acids Synthesis in Tobacco
por: Yang, Tianquan, et al.
Publicado: (2016)

A cryptic long-chain 3-ketoacyl-ACP synthase in the Pseudomonas putida F1 unsaturated fatty acid synthesis pathway
por: Dong, Huijuan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_umq5okoc4o2lkie5m97hlb1gog