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Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution

Small heat shock proteins (sHSPs) emerged early in evolution and occur in all domains of life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, HspB5, HspB8) are associated with neuromuscular disorders. The aim of this study is to investigate the evolutionary forces...

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Detalles Bibliográficos
Autores principales: Benndorf, Rainer, Velazquez, Ryan, Zehr, Jordan D., Pond, Sergei L. Kosakovsky, Martin, Jody L., Lucaci, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346038/
https://www.ncbi.nlm.nih.gov/pubmed/35678958
http://dx.doi.org/10.1007/s12192-022-01268-y