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Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution
Small heat shock proteins (sHSPs) emerged early in evolution and occur in all domains of life and nearly in all species, including humans. Mutations in four sHSPs (HspB1, HspB3, HspB5, HspB8) are associated with neuromuscular disorders. The aim of this study is to investigate the evolutionary forces...
Autores principales: | Benndorf, Rainer, Velazquez, Ryan, Zehr, Jordan D., Pond, Sergei L. Kosakovsky, Martin, Jody L., Lucaci, Alexander G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346038/ https://www.ncbi.nlm.nih.gov/pubmed/35678958 http://dx.doi.org/10.1007/s12192-022-01268-y |
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