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An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion

The abscopal effect without concomitant immunotherapy is a rare event, including among cases of lung cancer. Furthermore, the occurrence of limited abscopal effect for only a single lesion in the metastatic organ consistent with the irradiated organ would be an even more rare event. A 94‐year‐old ma...

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Autores principales: Sakaguchi, Tadashi, Ito, Kentaro, Fujiwara, Kentaro, Nishii, Yoichi, Ochiai, Satoru, Nomoto, Yoshihito, Hataji, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346180/
https://www.ncbi.nlm.nih.gov/pubmed/35761777
http://dx.doi.org/10.1111/1759-7714.14551
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author Sakaguchi, Tadashi
Ito, Kentaro
Fujiwara, Kentaro
Nishii, Yoichi
Ochiai, Satoru
Nomoto, Yoshihito
Hataji, Osamu
author_facet Sakaguchi, Tadashi
Ito, Kentaro
Fujiwara, Kentaro
Nishii, Yoichi
Ochiai, Satoru
Nomoto, Yoshihito
Hataji, Osamu
author_sort Sakaguchi, Tadashi
collection PubMed
description The abscopal effect without concomitant immunotherapy is a rare event, including among cases of lung cancer. Furthermore, the occurrence of limited abscopal effect for only a single lesion in the metastatic organ consistent with the irradiated organ would be an even more rare event. A 94‐year‐old man was diagnosed with advanced lung cancer with osteolytic bone metastases in his right iliac bone, and the right side of his axial vertebrae. After palliative radiation therapy to the right iliac lesion for pain relief without other anticancer therapy, the axial vertebral osteolytic lesion disappeared despite no reduction in the other lesions. This case furthers our understanding of the pathogenesis of the abscopal effect.
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spelling pubmed-93461802022-08-05 An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion Sakaguchi, Tadashi Ito, Kentaro Fujiwara, Kentaro Nishii, Yoichi Ochiai, Satoru Nomoto, Yoshihito Hataji, Osamu Thorac Cancer Case Reports The abscopal effect without concomitant immunotherapy is a rare event, including among cases of lung cancer. Furthermore, the occurrence of limited abscopal effect for only a single lesion in the metastatic organ consistent with the irradiated organ would be an even more rare event. A 94‐year‐old man was diagnosed with advanced lung cancer with osteolytic bone metastases in his right iliac bone, and the right side of his axial vertebrae. After palliative radiation therapy to the right iliac lesion for pain relief without other anticancer therapy, the axial vertebral osteolytic lesion disappeared despite no reduction in the other lesions. This case furthers our understanding of the pathogenesis of the abscopal effect. John Wiley & Sons Australia, Ltd 2022-06-27 2022-08 /pmc/articles/PMC9346180/ /pubmed/35761777 http://dx.doi.org/10.1111/1759-7714.14551 Text en © 2022 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Sakaguchi, Tadashi
Ito, Kentaro
Fujiwara, Kentaro
Nishii, Yoichi
Ochiai, Satoru
Nomoto, Yoshihito
Hataji, Osamu
An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion
title An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion
title_full An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion
title_fullStr An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion
title_full_unstemmed An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion
title_short An oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion
title_sort oldest‐old non‐small cell lung cancer patient with abscopal effect in a single lesion
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346180/
https://www.ncbi.nlm.nih.gov/pubmed/35761777
http://dx.doi.org/10.1111/1759-7714.14551
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