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Decreased steroidogenic enzyme activity in benign adrenocortical tumors is more pronounced in bilateral lesions as determined by steroid profiling in LC-MS/MS during ACTH stimulation test

OBJECTIVE: Large response of steroid precursors, including 17-hydroxyprogesterone, to adrenocorticotropic hormone (ACTH) has been described in adrenocortical tumors, suggesting the existence of intra-tumoral enzymatic deficiencies. This study aimed to compare steroidogenesis enzymes activity in unil...

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Detalles Bibliográficos
Autores principales:	Bonnet-Serrano, Fidéline, Barat, Maxime, Vaczlavik, Anna, Jouinot, Anne, Bouys, Lucas, Laguillier-Morizot, Christelle, Zientek, Corinne, Simonneau, Catherine, Larger, Etienne, Guignat, Laurence, Groussin, Lionel, Assié, Guillaume, Guibourdenche, Jean, Nicolis, Ioannis, Menet, Marie-Claude, Bertherat, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346343/ https://www.ncbi.nlm.nih.gov/pubmed/35731238 http://dx.doi.org/10.1530/EC-22-0063

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