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Macrophage polarization as a potential therapeutic target for atherosclerosis: a dynamic stochastic modelling study

We proposed a dynamic stochastic mathematical model to evaluate the role of macrophage polarization in plaque development. The dynamic process of macrophages from proliferation to death was simulated under different lipid microenvironments. The probability of macrophage phenotypic switching was desc...

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Detalles Bibliográficos
Autores principales: Liu, Mengchen, Cai, Yan, Pan, Jichao, Peter, Karlheinz, Li, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346359/
https://www.ncbi.nlm.nih.gov/pubmed/35950200
http://dx.doi.org/10.1098/rsos.220239