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Accumulation of poly (adenosine diphosphate-ribose) by sustained supply of calcium inducing mitochondrial stress in pancreatic cancer cells

BACKGROUND: The biochemical phenomenon defined as poly adenosine diphosphate (ADP)-ribosylation (PARylation) is essential for the progression of pancreatic cancer. However, the excessive accumulation of poly ADP-ribose (PAR) induces apoptosis-inducing factor (AIF) release from mitochondria and energ...

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Detalles Bibliográficos
Autores principales:	Jeong, Keun-Yeong, Sim, Jae Jun, Park, Minhee, Kim, Hwan Mook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2022
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346456/ https://www.ncbi.nlm.nih.gov/pubmed/36158271 http://dx.doi.org/10.3748/wjg.v28.i27.3422

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