A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation

The primary cilium constitutes an organelle that orchestrates signal transduction independently from the cell body. Dysregulation of this intricate molecular architecture leads to severe human diseases, commonly referred to as ciliopathies. However, the molecular underpinnings how ciliary signaling...

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Detalles Bibliográficos
Autores principales: Hansen, Jan N, Kaiser, Fabian, Leyendecker, Philipp, Stüven, Birthe, Krause, Jens‐Henning, Derakhshandeh, Fatemeh, Irfan, Jaazba, Sroka, Tommy J, Preval, Kenley M, Desai, Paurav B, Kraut, Michael, Theis, Heidi, Drews, Anna‐Dorothee, De‐Domenico, Elena, Händler, Kristian, Pazour, Gregory J, Henderson, David J P, Mick, David U, Wachten, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346484/
https://www.ncbi.nlm.nih.gov/pubmed/35695071
http://dx.doi.org/10.15252/embr.202154315

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